OS writes on the contribution our wobbling cousins from under the sea are making to the fight for a cure.
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Addex Pharmaceuticals announced that it has completed the first part of a two-part Phase I clinical trial to evaluate the newly developed modified release formulation of ADX48621. ADX48621 is scheduled to start a Phase IIa proof of concept study for the treatment of levodopa associated dyskinesia in Parkinson’s disease during the first half of 2009. Chief Medical Officer Charlotte Keywood said: “we are pleased by the progress of ADX48621 and are preparing to start the Phase IIa proof of concept trial to study its utility in Parkinson’s disease dyskinesia next year.”
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The first in a series of articles by our resident Life Coach.
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WobblyWilliams.com have launched on the social networking site Facebook. The objective of the group is to raise awareness of the condition and to provide a forum for people to suggest how the website can be improved and how our goals of raising awareness and financing research into a cure can be better achieved. As with all these things the group is only as good as its members so sign up today!
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Scientists are testing whether vitamin D supplements can ease symptoms of Parkinson's disease. A US team found 55% of Parkinson's patients had insufficient levels of vitamin D, compared to 36% of healthy elderly people. However, the Emory University researchers do not yet know if the vitamin deficiency is a cause or the result of having Parkinson's. More here,
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That Isaacs guy is such a show off!!! More here.
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Researchers have discovered that as embryonic stem cells turn into different cell types, there are dramatic corresponding changes in the order in which DNA is replicated and reorganised. The findings bridge a critical knowledge gap for stem cell biologists, enabling them to better understand the enormously complex process by which DNA is repackaged during differentiation - when embryonic stem cells, jacks of all cellular trades, lose their anything-goes attitude and become masters of specialised functions.
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The WobblyWilliams.com You Tube channel has gone live. The channel is a bit light on content at the moment but includes the coverage on ITV's The 5.30 Show allowing viewers outside the UK to see my revolting children!
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The Parkinson’s Disease Society has announced funding of £170,000 to the School of Pharmacy in London, to research the potential benefits of exendin-4 (EX-4), a hormone found in the salivary gland of venomous lizard, the Gila monster. Parkinson’s is caused by the death of dopamine producing nerve cells in the brain, and scientists have always believed that the brain is unable to protect or repair itself. Recent research suggests that this may be only partially true, and stimulating the brain’s natural protective or repair mechanisms (neuroprotection), offers an exciting new approach to treating conditions like Parkinson’s. Details here.
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Cells taken from men's testicles seem as versatile as the stem cells derived from embryos, researchers reported in what may be yet another new approach in a burgeoning scientific field. The new type of stem cells could be useful for growing personalized replacement tissues, according to a study in Thursday's issue of the journal Nature. But because of their source, their highest promise would apply to only half the world's population: men. Don't worry girls, I won't see you go short!
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